Regenerative GF Complete

In just one treatment, produce the industry's most advanced cosmetic result and simultaneously restore the natural glow of holistic skin health.


Clinically proven by DOCTORS

Now available to PROFESSIONALS

BEFORE/AFTER one 50% Glycolic PEEL + Regenerative GF Complete application.

Skin Authority Regenerative GF Complete

Regenerative GF Complete is for professional use only and  REQUIRES PROFESSIONAL CERTIFICATION. Contact for details.

Elevate the visible results pre and post microneedling, laser, peels, dermaplaning, and advanced cosmetic procedures for the ultimate lifting and firming, while accelerating healthy skin recovery and restoring daily skin function.


Provides the optimum ratio of regenerative growth factor resources the skin needs to speed skin recovery and cellular renewal pre- and post- procedures. 


Remodels damaged dermal tissue at deeper level to reverse visible signs of loss of elasticity, volume, skin tone, and inflammation.



Offers effective natural treatment alternatives for improving chronic skin conditions caused by drug/radiation therapy, diabetes, rosacea, acne, and other immune compromised concerns.



Boosts skin immunity for ongoing defense and repair from environmental aggressors and pathogens.



GFs help cells divide and multiply faster. This leads to a thicker, firmer, and tighter epidermis and dermis for a more lifted, volumized appearance.



GFs can also minimize scarring during wound healing.


The Ladies Holding Skin Authority Skincare Products

What makes Regenerative GF Complete Unique?

A patented proprietary blend of anti-inflammatory Growth Factors, cytokines, and glycans, in the precise ratio, scientifically shown to accelerate healing and regenerate collagen, glucosaminoglycans, and elastin in connective tissue cells. Supplementing the correct level of specifically needed GFs induces repair of dermal tissue reversing visible signs of aging, reducing inflammation and restoring health within the skin. Our GFs deliver messages encouraging cell proliferation, differentiation, and healing, while cytokines deal with immune and inflammatory responses. 

List of Growth Factors in SGF-4 Technology and Their Functions

How does it work?

Regenerative GF Complete is designed to deliver its patented combination of natural skin renewing GFs and cytokines to the deepest level of penetration and absorption triggering regeneration and repair at a molecular level in the skin. Unlike large collagen and elastin molecules which have difficulty penetrating, the specific Growth Factors and Cytokines selected for GF Complete create cell-to-cell signaling pathways which allow them to communicate deeply into the skin reaching the fibroblasts in the thick connective tissue of the dermis. They also posses the added advantage of penetrating mostly through vertical pathways such as the pore of hair follicles, sweat glands or micro lesions in the stratum corneum. So using GF Complete with penetrating procedures such as micro needling, micro dermabrasion, peels, and laser can further advance the acceleration of GF Complete healing agents. GF Complete has been designed with a unique delivery system of conditioned media enriched with phospholipids to further the absorption of GFs and Cytokines. GF Complete harnesses Glycosaminoglycans which stabilize GFs and act as super moisturizers to hydrate the dermal layer from within, penetrating where simple moisturizers cannot. As GF Complete’s regenerative blend penetrates, it enhances the immune response triggering secretion of additional vital growth factors necessary to stimulate cell repair, supplement the healing process, and increase the resilient volume of the extracellular matrix of the skin.


Before and After Comparison of Microneedling Treatment with Regenerative GF Complete
Acne & Scarring With Microneedling Treatment.
(LEFT) Before treatment. (RIGHT) After Microneedling Treatment with Regenerative GF Complete application and 6 weeks daily Wrinkle Reversing Serum home care application.

Before and After Comparison of Glycolic Peel Treatment with Regenerative GF Complete
Discoloration & Tone With Glycolic Peel Treatment.
(LEFT) Before treatment. (RIGHT) After 50% / 2.5ph Glycolic Peel Treatment with Regenerative GF Complete application (face & neck).

Before and After Comparison of Radiotherapy Session with Regenerative GF Complete
Radiotherapy for HER2 Breast Cancer.
(LEFT) Day 1 post 22nd Radiotherapy session, Day 1 Regenerative GF Complete application. (RIGHT) Day 18 post 25th Radiotherapy session, Day 21 post Regenerative GF Complete application.

Before and After Comparison of wound pre-debridement with application of Regenerative GF Complete
Artery Bypass Graft With Saphenous Vein With Type 2 Diabetes.
(LEFT) Day 1 wound pre-debridement with application of Regenerative GF Complete on Day 4. (RIGHT) Month 3 post Regenerative GF Complete application.

Images courtesy of Georgia Vadarli & Maria Angelo-Khattar, Plastic Surgery Consultancies, Greece & UAE. Additional images courtesy of Dr. Ahmed Al-Qahtani. 

How is it different from current approaches to skin regeneration?

Most topical products or treatments involve either: (1) damaging the skin causing trauma, which sends the skin into an inflammatory response in order to produce repair resources i.e. collagen and elastin; or (2) rely on hydrating ingredients, i.e. hyaluronic acid and glucosamine, to produce a temporary visible plumping of the skin, along with using  plant or animal based GF resources which produce an antioxidant affect, but don’t improve the molecular structure of human skin. This product was developed by immunologists who study the science of the body’s repair and prevention systems. Our immunologists understand through science that the bodies mechanism of successful skin healing and repair requires the cell to transition from the inflammatory stage to a granulation stage of repair and growth. Documented research shows the stimulation of fibroblasts occurs when specific levels and combinations of human GFs and Cytokines, in the appropriate delivery medium, signal the molecules required to induce healing and regeneration. Signs of aging reversal and skin repair is visibly apparent and longer lasting. Staying in recurring states of inflammatory response can be counteractive to the goal of healthy improvement. Intervention to reduce length and scale of inflammation is critical to sustained improvement and health. Regenerative GF Complete is ideal for individuals seeking non-surgical and less aggressive treatments with no-to-minimal downtime, but demand a high level of results. When combined with Regenerative GF Complete, patients surveyed express high levels of satisfaction with the treatment experience, less downtime and a feeling of more safety.

Regenerative GF Complete Clinical Assessment
Regenerative GF Complete Subject Assessment
Customer Evaluation of Wrinkle Reversing Serum

How does it impact healing time following procedures?

With Regenerative GF Complete application following CO2 laser procedures, the average healing time was reduce from 12 days to 6. Physicians reported seeing improved results over laser alone with significant collagen production, improved healing and shorter downtime. When used in conjunction with microneedling or peels, the advantages of applying GF Complete were: (1) no open wounds; (2) short duration of treatment; and (3) quick healing and recovery time with no to minimal downtime. They were also able to shorten the interval of treatment to 2 sessions vs 4 sessions and 2-3 weeks versus 4-6. However, the interval of 4-6 weeks should be respected based upon professional assessment and patient baseline condition.

30-year old female immediately after Microneedling Treatment with Regenrative GF Complete application
Microneedling Treatment.
30-year old female immediately after Microneedling Treatment with Regenrative GF Complete application.

Before and After Treatment Comparison of Regenerative GF Complete application
Fractional CO2 Laser Treatment.
(LEFT) 25-year old male before laster treatment. (RIGHT) Two months after treatment with Regenerative GF Complete application.

How does Regenerative GF Complete compare to PRP?

PRP (Platelet Rich Plasma) was a breakthrough in the 1980’s as an original means of having a general source for human growth factors particularly for the purpose of potential bone healing. However, after many trials, PRP was not able to deliver consistent results and was moved to a more cosmetic use. In the three decades since that time, molecular biology and biotechnology has advanced the ability to understand the unique role of specific growth factors in producing certain healing resources and isolate those specific growth factors to create very targeted approaches to accelerate healing and repair. GF Complete leverages the biotechnology to sort specific GF types in the right ratio to get a very specific outcome for healing and rejuvenation. We can also control the “dose” or ratio of Growth Factor vs. PRP. For example, we use different growth factor complexes with different ratios in our retail product Wrinkle Reversing Serum designed for sustaining improved results at home versus GF Complete which is designed for more invasive skin damage to greatly reduce inflammatory response, enhance the healing and repair process. PRP in cosmetic use doesn’t have that same capability or the ability to stress fibroblasts in our skin to produce additional growth factors for continual improvement in the way GF Complete does. Most importantly GF Complete doesn’t require blood preparation which reduces concerns about contamination and spread of infectious disease.


How does Regenerative GF Complete compare to Stem Cell Sources?

We named the professional product Regenerative GF Complete because it is the most complete skin care solution in terms of repairing the damage seen in the most widespread skin conditions while restoring healthy function of the cell for prevention and preservation. It clinically outperforms other skin care ingredient approaches:

Adipose Stem Cells.

Adipose or fat stem cells are easy to grow in lab, abundant and cheaper to produce. Adipose stem cells are commonly sourced from liposuction waste and have not been studied as thoroughly as fibroblasts.  Adipose stem cells perform endocrine functions in our body and secrete hormones into the bloodstream, which may have unintended effects on tissues. They are more highly inflammatory releasing several GFs which may disrupt healthy biochemical pathways in the body.  

Cell Lysates. 

Cell lysates are liquids that result from a process of breaking down cell membranes. Often controversial because they can be sourced from pre-embryonic sources including unfertilized human eggs or harvested from aborted fetal tissues. But the larger science concern is due to the treatment process which makes it hard to filter intact GFs.   

Animal Derived GF.

Many brands promote Animal Derived Growth factors such as sheep placenta, deer cord blood or snail slime. There is little published skin science other than that provided by manufacturers to support their use. There may be reaction concerns as these GFs are foreign to the human body. For example, snail mucosa especially causes inflammatory reactions. Plus, they cross-react with common household dust mites, putting you at risk for allergic reactions and other side effects. 

Plant Derivatives.

Plant-derived growth factors are botanicals which are commonly used ingredients in skin care. They can have anti-inflammatory and antioxidant properties and may also have antimicrobial components. Plant derivatives cannot achieve the same effect as human GFs because plant and human organisms speak a fundamentally different biological language. Human Growth factors work by communicating with cells and encouraging them to work in a specific way to rejuvenate function. 


Although exosome-containing products are available in the marketplace, some companies that make them have received FDA warning letters. While Exosomes hold potential for helping to identify areas which may harbor cancer, there is no process for determining the quality, quantity or health condition of the Growth Factors contained within the Exosomes. FDA safety concerns could limit the commercial potential of exosome-containing skin care topicals for the near term.


Growth Factor Range by Skin Authority (SGF-4 Technology™)


GF Complete

Regenerative GF Complete with SGF-4 Technology

Regenerative GF Complete, 4.0ml. PROFESSIONAL CERTIFICATION REQUIRED. Contact for details.


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1. Fernandes D. Percutaneous collagen induction: an alternative to laser resurfacing. Aesthet Surg J. 2002;22(3):307-309. 2. Fernandes D. Minimally invasive percutaneous collagen induction. Oral Maxillofac Surg Clin. 2005;17(1):51-63. 3. Aust MC, Fernandes D, Kolokythas P, Kaplan HM, Vogt PM. Percutaneous collagen induction therapy: an alternative treat- ment for scars, wrinkles, and skin laxity. Plast Reconstr Surg. 2008;121(4):1421-1429. 4. Fernandes D, Signorini M. Combating photoaging with percutane- ous collagen induction. Clin Dermatol. 2008;26(2):192-199. 5. El-Domyati M, Barakat M, Awad S, Medhat W, El-Fakahany H, Farag H. Multiple microneedling sessions for minimally inva- sive facial rejuvenation: an objective assessment. Int J Dermatol. 2015;54(12):1361-1369. 6. Hogan S, Velez MW, Ibrahim O. Microneedling: a new approach for treating textural abnormalities and scars. Semin Cutan Med Surg. 2017;36(4):155-163. 7. McCrudden MTC, McAlister E, Courtenay AJ, González-Vázquez P, Raj Singh TR, Donnelly RF. Microneedle applications in improving skin appearance. Exp Dermatol. 2015;24(8):561-566. 8. Kim SE, Lee J-H, Kwon HB, Ahn B-J, Lee A-Y. Greater collagen deposition with the microneedle therapy system than with intense pulsed light. Dermatol Surg. 2011;37(3):336-341. 9. Fabbrocini G, Fardella N, Monfrecola A, Proietti I, Innocenzi D. Acne scarring treatment using skin needling. Clin Exp Dermatol. 2009;34(8):874-879. 10. Sasaki GH. Micro-needling depth penetration, presence of pigment particles, and fluorescein-stained platelets: clinical usage for aes- thetic concerns. Aesthet Surg J. 2016;37(1):71-83. 11. Hou A, Cohen B, Haimovic A, Elbuluk N. Microneedling: a compre- hensive review. Dermatol Surg. 2017;43(3):321-339. 12. Ramaut L, Hoeksema H, Pirayesh A, Stillaert F, Monstrey S. Microneedling: Where do we stand now? A systematic review of the literature. J Plast Reconstr Aesthet Surg. 2018;71(1):1-14. 13. Iriarte C, Awosika O, Rengifo-Pardo M, Ehrlich A. Review of ap- plications of microneedling in dermatology. Clin Cosmet Investig Dermatol. 2017;10:289. 14. Cohen BE, Elbuluk N. Microneedling in skin of color:A review of uses and efficacy. J Am Acad Dermatol. 2016;74(2):348-355. 15. Sharma D. Microneedles: an approach in transdermal drug delivery: a Review. PharmaTutor. 2018;6(1):7-15. 16. Waghule T, Singhvi G, Dubey SK, et al. Microneedles: A smart ap- proach and increasing potential for transdermal drug delivery sys- tem. Biomed Pharmacother. 2019;109:1249-1258. 17. Mohammed YH, Yamada M, Lin LL, et al. Microneedle enhanced delivery of cosmeceutically relevant peptides in human skin. PLoS One. 2014;9(7):e101956. 18. Bora P, Kumar L, Bansal AK. Microneedle technology for advanced drug delivery: Evolving vistas. Review Article, Department of Pharmaceutical Technology, NIPER, CRIPS. 2008;9(1). 19. Larrañeta E, Rebecca EML, Woolfson AD, Ryan FD. Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development. Mater Sci Eng R Rep. 2016;104:1-32. 20. Serrano G, Almudéver P, Serrano JM, et al. Microneedling dilates the follicular infundibulum and increases transfollicular absorp- tion of liposomal sepia melanin. Clin Cosmet Investig Dermatol. 2015;8:313 . 21. Zhao Z, Chen Y, Shi Y. Microneedles: a potential strategy in trans- dermal delivery and application in the management of psoriasis. RSC Adv. 2020;10(24):14040-14049. 22. Werner S, Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev. 2003;83(3):835-870. 23. Barrientos S, Stojadinovic O, Golinko MS, Brem H, Tomic-Canic M. Growth factors and cytokines in wound healing. Wound Repair Regen. 2008;16(5):585-601. 24. Penn JW, Grobbelaar AO, Rolfe KJ. The role of the TGF-β family in wound healing, burns and scarring: a review. Int J Burns Trauma. 2012;2(1):18-28. 25. Sundaram H, Mehta RC, Norine JA, et al. Topically applied physio- logically balanced growth factors: a new paradigm of skin rejuvena- tion. J Drugs Dermatol. 2009;8(5 suppl):4-13. 26. Gilbert RWD, Vickaryous MK, Viloria-Petit AM. Signalling by trans- forming growth factor beta isoforms in wound healing and tissue regeneration. J Dev Biol. 2016;4(2):21. 27. Pakyari M, Farrokhi A, Maharlooei MK, Ghahary A. Critical role of transforming growth factor beta in different phases of wound heal- ing. Adv Wound Care. 2013;2(5):215-224. 28. Baldelli CMF, Ruella M, Scuderi S, et al. A short course of granu- locyte–colony-stimulating factor to accelerate wound repair in pa- tients undergoing surgery for sacrococcygeal pilonidal cyst: proof of concept. Cytotherapy. 2012;14(9):1101-1109.  29. Pierce GF, Mustoe TA, Altrock BW, Deuel TF, Thomason A. Role of platelet-derived growth factor in wound healing. J Cell Biochem. 1991;45(4):319-326. 30. Zarei F, Soleimaninejad M. Role of growth factors and biomaterials in wound healing. Artific Cells Nanomed Biotechnol. 2018;46(suppl 1):906-911. 31. Lee HJ, Lee EG, Kang S, Sung J-H, Chung H-M, Kim DH. Efficacy of microneedling plus human stem cell conditioned medium for skin rejuvenation: a randomized, controlled, blinded split-face study. Ann Dermatol. 2014;26(5):584-591. 32. Seo KY, Kim DH, Lee SE, Yoon MS, Lee HJ. Skin rejuvenation by microneedle fractional radiofrequency and a human stem cell con- ditioned medium in Asian skin: a randomized controlled investigator blinded split-face study. J Cosmet Laser Ther. 2013;15(1):25-33. 33. Mehta RC, Fitzpatrick RE. Endogenous growth factors as cosme- ceuticals. Dermatol Ther. 2007;20(5):350-359. 34. Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth factors: a pilot study. Journal of Cosmetic and Laser Therapy. 2003;5(1):25-34. 35. Singh A, Yadav S. Microneedling: Advances and widening horizons. Indian Dermatol Online J. 2016;7(4):244-254. 36. Zeitter S, Sikora Z, Jahn S, et al. Microneedling: Matching the results of medical needling and repetitive treatments to maximize potential for skin regeneration. Burns. 2014;40(5):966-973. 37. AQ Skin Solutions Introduces Growth Factor Induced Therapy. THE Aesthetic Guide 2017. 38. Klassen AF, Cano SJ, Schwitzer JA, Scott AM, Pusic AL. FACE-Q scales for health-related quality of life, early life impact, satisfaction with outcomes, and decision to have treatment: development and validation. Plast Reconstr Surg. 2015;135(2):375-386. 39. Klassen AF, Cano SJ, Scott AM, Pusic AL. Measuring outcomes that matter to face-lift patients: development and validation of FACE-Q appearance appraisal scales and adverse effects checklist for the lower face and neck. Plast Reconstr Surg. 2014;133(1):21-30. 40. Klassen A, Cano S, Scott A, Snell L, Pusic A. Measuring patient-re- ported outcomes in facial aesthetic patients: development of the FACE-Q. Facial Plast Surg. 2010;26(04):303-309. 41. Nouveau-Richard S, Yang Z, Mac-Mary S, et al. Skin ageing: a com- parison between Chinese and European populations: a pilot study. J Dermatol Sci. 2005;40(3):187-193. 42. Vashi NA, Maymone MBDC, Kundu RV. Aging differences in ethnic skin. J Clin Aesthet Dermatol. 2016;9(1):31. 43. Chung JH. Photoaging in Asians. Photodermatol Photoimmunol Photomed. 2003;19(3):109-121. 44. Gold MH, Goldman MP, Biron J. Efficacy of novel skin cream con- taining mixture of human growth factors and cytokines for skin re- juvenation. J Drugs Dermatol. 2007;6(2):197. 45. Gold MH, Goldman MP, Biron J. Human growth factor and cytokine skin cream for facial skin rejuvenation as as- sessed by 3D in vivo optical skin imaging. J Drugs Dermatol. 2007;6(10):1018-1023. 46. Lee MJ, Kim J, Lee KI, et al. Enhancement of wound healing by se- cretory factors of endothelial precursor cells derived from human embryonic stem cells. Cytotherapy. 2011;13(2):165-178. 47. Zhang YI, Wang T, He J, Dong J. Growth factor therapy in patients with partial-thickness burns: a systematic review and meta-analy- sis. Int Wound J. 2016;13(3):354-366. 48. Akita S, Akino K, Imaizumi T, et al. The quality of pediatric burn scars is improved by early administration of basic fibroblast growth factor. J Burn Care Res. 2006;27(3):333-338. 49. Weshahy RH, Aly DG, Shalaby S, Mohammed FN, Sayed KS. Clinical and histological assessment of combined fractional CO2 laser and growth factors versus fractional CO2 laser alone in the treatment of facial mature burn scars: a pilot split-face study. Lasers Surg Med. 2020. [Epub ahead of print]. 50. Bonin-Debs AL, Boche I, Gille H, Brinkmann U. Development of secreted proteins as biotherapeutic agents. Exp Opin Biol Ther. 2004;4(4):551-558. 51. Obagi ZE.The art of skin health restoration and rejuvenation. 2014: Crc Press. 52. Lee J, Blaber M. Increased functional half-life of fibroblast growth factor-1 by recovering a vestigial disulfide bond. J Proteins Proteomics. 2010;1(2):37-42.